CTNND1 抗体 (AA 470-712)
Quick Overview for CTNND1 抗体 (AA 470-712) (ABIN7112388)
抗原
See all CTNND1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-712
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原理
- CTNND1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 470-712aa
Immunogen: catenin, delta 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
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别名
- CTNND1
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背景
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Synonyms: Catenin delta-1|Cadherin-associated Src substrate (CAS)|p120 catenin (p120(ctn))|p120(cas)|CTNND1|KIAA0384
Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway(By similarity). Associates with and regulates the cell adhesion properties of both C-, E-and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
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分子量
- 105 kDa, 66 kDa
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UniProt
- O60716
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
抗原
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